Thank you for sharing our content. A message has been sent to your recipient's email address with a link to the content webpage. Your name: is required Error: This is required. Your email: is required Error: This is required Error: Not a valid value. Send to: is required Error: This is required Error: Not a valid value. Over 65? Pregnant or planning a pregnancy? Consumer medicine information CMI Reporting side effects Data sources Disclaimer What it is used for Prevention of thrombo-embolic disorders of venous origin in patients undergoing orthopaedic and general surgery.
How to take it The way to take this medicine is: Extracorporeal Circulation - Haemodialysis. Always read the label. If symptoms persist see your healthcare professional. Do I need a prescription? What is the medicines and poisons schedule? How to take it The way to take this medicine is: Subcutaneous. Healthdirect 24hr 7 days a week hotline 24 hour health advice you can count on The clotting process is complicated and begins when blood cells called platelets clump together and produce chemicals that activate the clotting process.
The final part of this process involves a substance called thrombin being activated to produce a protein called fibrin. Fibrin binds the platelets together, forming a blood clot. This is the body's natural way of repairing itself. Sometimes, however, a blood clot can form abnormally within the blood vessels. This is known as a thrombus. It can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus.
The embolus may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. This is known as a thromboembolism. Some people have an increased tendency for blood clots to form within the blood vessels. This is usually due to a disturbance in the blood flow within the blood vessels.
For example, in coronary artery disease, fatty deposits atherosclerosis on the walls of the coronary arteries can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. When a clot has formed in a coronary artery this reduces the flow of blood to the heart and causes chest pain angina. It can also result in a heart attack. Slow blood flow in the leg and pelvic veins can also result in clots forming in these veins deep vein thrombosis. These clots can break off and travel to the lungs pulmonary embolism.
Being immobile for long periods of time, for example due to a severe medical condition or following surgery, can increase the risk of these types of blood clot, as can pregnancy, obesity and certain blood disorders. Enoxaparin can prevent and treat these types of abnormal blood clots.
It works by inactivating thrombin in the clotting process described above. This stops the formation of fibrin, the essential component of blood clots. Clexane is administered by injection under the skin of the abdomen subcutaneous injection. The dose and length of treatment used will depend on the nature of the clot being treated or prevented.
Enoxaparin is not known to be harmful if used during pregnancy. Clexane is often used to prevent and treat blood clots in pregnant women. The use of enoxaparin has not been studied in women who are breastfeeding. However, it is unlikely to pass into breast milk and even if it did, it would be inactivated in the gut of the baby. The medicine is not expected to be harmful to a nursing infant if it is used to treat mothers who are breastfeeding.
Medicines and possible side-effects can affect individual people in different ways. The following are some of the side-effects which may be associated with this medicine. Just because a side-effect is listed here, this does not mean that everyone who uses this medicine will experience it, or any side-effect. If you are concerned about side-effects or experience an adverse reaction from your medicine, consult your GP. You should read the patient information leaflet that is supplied with your medication for more information about side effects associated with Clexane.
You can find a copy of this here. If you think you have experienced side effects from this medicine, you can report them using the yellow card scheme. You should check with your pharmacist before taking any new medicines while you're taking Clexane, to make sure that the combination is safe.
In July a new Clexane device with safety lock injection replaced the old Clexane device without safety lock injection.
If you click on the arrow below, you can watch 2 videos, one for the Clexane device with safety lock and one for the old Clexane device without a safety lock. If this is not possible, your GP may be able to arrange for a nurse to give you the injections in your home, or for you to go to a clinic.
Like all medicines, Clexane can cause side effects, although not everyone gets them. Common side effects include pain, itch, swelling or rash at the injection site. These may go away with time. Tell your doctor if any side effects continue to bother you. Taking Clexane means that your blood takes longer to form clots. This can increase your risk of bleeding. The benefits of using anticoagulants usually outweigh the risks of bleeding and your doctor will consider this before starting treatment.
You might bleed or bruise more easily while you are taking Clexane.
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